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| Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies, Cell, 183 (1), pp. 126-142.e17, October, 01, 2020. Abstract CD19-directed immunotherapies are clinically effective for treating B cell malignancies but also cause a high incidence of neurotoxicity. A subset of patients treated with chimeric antigen receptor (CAR) T cells or bispecific T cell engager (BiTE) antibodies display severe neurotoxicity, including fatal cerebral edema associated with T cell infiltration into the brain.
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| Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids, Nature Communications, 13, 430 (2022) |
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Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy, Nature Communications, 13, 2306 (2022) |
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A Fully-Human Antibody Specifically Targeting a Membrane-Bound Fragment of CADM1 Potentiates the T Cell-Mediated Death of Human Small-Cell Lung Cancer Cells, International Journal of Molecular Sciences, 23.13 (2022) |
| Generation and Next-Generation Sequencing-Based Characterization of a Large Human Combinatorial Antibody Library, International Journal of Molecular Sciences, 2023 |
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A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1. Journal of Clinical Investigation, 2023 |
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A novel bispecific antibody dual-targeting approach for enhanced neutralization against fast-evolving SARS-CoV-2 variants. Frontiers in Immunology, 2023 Link : https://doi.org/10.3389/fimmu.2023.1271508
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제품명 / Cat. No.
ADAM™ CellT / ADAM™ CellT
포커스
자동 포커싱
LED
4W Green LED
무게
7.0 Kg
크기 (L X W X H)
277 X 276 X 270 mm
분석 시간
< 25 sec/test (4 ch)
주입량
13 µL/test (4 ch)
측정량
3.4 µL/test (4ch)
측정 범위
5 X 10E4 ~ 4 X 10E6 cells/mL (PI)
5 X 10E4 ~ 2 X 10E7 cells/mL (AO/PI)
데이터 백업 및 복구용 추가 저장장치
4TB
라이프사이언스 / ADAM™ CellT
Bead Calibration 결과가 범위를 벗어 납니다
라이프사이언스 / ADAM™ CellT
영상에 이물이 많이 관찰 됩니다.